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Ilatreotide

Ilatreotide (SDZ CO61), glycated somatostatin derivative, is a highly potent glycated analog of somatostatin with improved oral activity. Ilatreotide can suppress the fasting level and postprandial release of several gastrointestinal and pancreatic hormones. Ilatreotide can be used for the research of gastroenteropancreatic tumors[1][2][3].

Product Specifications

CAS Number

[119719-11-8]

Product Name Alternative

SDZ CO 611

UNSPSC

12352209

Target

Somatostatin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ilatreotide.html

Solubility

10 mM in DMSO

Smiles

C[C@@H](O)[C@H]1C(N[C@H](C(N[C@@H]([C@H](O)C)CO)=O)CSSC[C@H](NC([C@H](NC[C@]2(O)[C@@H](O)[C@H](O[C@@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)[C@H](O)CO2)CC4=CC=CC=C4)=O)C(N[C@@H](CC5=CC=CC=C5)C(N[C@H](CC6=CNC7=CC=CC=C76)C(N[C@@H](CCCCN)C(N1)=O)=O)=O)=O)=O

Molecular Formula

C61H86N10O20S2

Molecular Weight

1343.52

References & Citations

[1]Drum, et al. Use of somatostatin analogs in myocardial perfusion imaging. Patent. WO2008143958 A1.|[2]Nelson-Piercy C, et al. Effect of a new oral somatostatin analog (SDZ CO 611) on gastric emptying, mouth to cecum transit time, and pancreatic and gut hormone release in normal male subjects. J Clin Endocrinol Metab. 1994 Feb;78 (2) :329-36.|[3]Albert R, et al. SDZ CO 611: a highly potent glycated analog of somatostatin with improved oral activity. Life Sci. 1993;53 (6) :517-25.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P2229/Ilatreotide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P2229/

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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