T338C Src-IN-1
T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C (IC50=111 nM) relative to WT c-Src (10-fold increase) .
Product Specifications
CAS Number
1351926-90-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Src
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/T338C-Src-IN-1.html
Solubility
10 mM in DMSO
Smiles
NC1=C2C(N(C(C)C)N=C2CC3=CC(NS(=O)(C=C)=O)=CC=C3)=NC=N1
Molecular Formula
C17H20N6O2S
Molecular Weight
372.44
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108 (37) :15046-52.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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