Rapastinel
Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator with partial agonist properties.
Product Specifications
CAS Number
[117928-94-6]
Product Name Alternative
GLYX-13
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Rapastinel.html
Purity
99.78
Solubility
DMSO : ≥ 32 mg/mL
Smiles
O=C(N(CCC1)[C@@H]1C(N[C@H](C(N)=O)[C@H](O)C)=O)[C@H](CCC2)N2C([C@@H](N)[C@H](O)C)=O
Molecular Formula
C18H31N5O6
Molecular Weight
413.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Burgdorf J, et al. The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus. Neuroscience. 2015 Nov 12;308:202-11.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
NMDA Receptor
Available Sizes
Curated Selection
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