AGN 205327
Product Specifications
UNSPSC Description
AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RARα/β/γ respectively; no inhibition on RXR.
IC50 value: 3766/734/32 nM for RARα/β/γ
Target: RAR agonist
Target Antigen
Autophagy; RAR/RXR
Type
Reference compound
Related Pathways
Autophagy;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/agn-205327.html
Solubility
10 mM in DMSO
Smiles
CC1(C)CCC(C)(C)C2=C1C=CC(/C(C3=CC4=CC(C(O)=O)=CC=C4N3)=N\O)=C2
Molecular Weight
390.47
References & Citations
[1]Preferential binding of synthetic retinoid analogs to subtypes of RAR.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-16685/AGN-205327-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-16685/
Clinical Information
No Development Reported
CAS Number
2070018-29-8
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS623616-01 0.1 mg
SARS, Spike Protein (Severe Acute Respiratory Syndrome, SARS-CoV, SARS Associated Coronavirus)
Ask
View Details 
MBS623616-02 5x 0.1 mg
SARS, Spike Protein (Severe Acute Respiratory Syndrome, SARS-CoV, SARS Associated Coronavirus)
Ask
View Details ARP34965_P050-Biotin 100 µL
CHRNA4 Antibody - N-terminal region: Biotin (ARP34965_P050-Biotin)
Ask
View Details