Emiglitate

Emiglitate (BAY o 1248) is a potent, selective and competitive inhibitor of α-glucoside hydrolase.

Product Specifications

CAS Number

[80879-63-6]

Product Name Alternative

BAY o 1248

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/EMIGLITATE.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(OCC)C1=CC=C(OCCN2[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C2)C=C1

Molecular Formula

C17H25NO7

Molecular Weight

355.38

References & Citations

[1]Mosén H, et al. Nitric oxide inhibits, and carbon monoxide activates, islet acid alpha-glucoside hydrolase activitiesin parallel with glucose-stimulated insulin secretion. J Endocrinol. 2006 Sep;190 (3) :681-93.|[2]Lembcke B, et al. Lysosomal storage of glycogen as a sequel of alpha-glucosidase inhibition by the absorbed deoxynojirimycin derivative emiglitate (BAYo1248) . A drug-induced pattern of hepatic glycogen storage mimicking Pompe's disease (glycogenosis type II) . Res Exp Med (Berl) . 1991;191 (6) :389-404.