Emiglitate
Emiglitate (BAY o 1248) is a potent, selective and competitive inhibitor of α-glucoside hydrolase.
Product Specifications
CAS Number
80879-63-6
Product Name Alternative
BAY o 1248
UNSPSC
12352005
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/EMIGLITATE.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(OCC)C1=CC=C(OCCN2[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C2)C=C1
Molecular Formula
C17H25NO7
Molecular Weight
355.38
References & Citations
[1]Mosén H, et al. Nitric oxide inhibits, and carbon monoxide activates, islet acid alpha-glucoside hydrolase activitiesin parallel with glucose-stimulated insulin secretion. J Endocrinol. 2006 Sep;190 (3) :681-93.|[2]Lembcke B, et al. Lysosomal storage of glycogen as a sequel of alpha-glucosidase inhibition by the absorbed deoxynojirimycin derivative emiglitate (BAYo1248) . A drug-induced pattern of hepatic glycogen storage mimicking Pompe's disease (glycogenosis type II) . Res Exp Med (Berl) . 1991;191 (6) :389-404.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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