P1

P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria, such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae[1].

Product Specifications

CAS Number

[675123-75-8]

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/p1.html

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CS)C(N[C@@H]([C@H](O)C)C(N[C@@H](CS)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N

Molecular Formula

C65H118N20O19S2

Molecular Weight

1547.89

References & Citations

[1]Crawford MA, et al. Disparate Regions of the Human Chemokine CXCL10 Exhibit Broad-Spectrum Antimicrobial Activity against Biodefense and Antibiotic-Resistant Bacterial Pathogens. ACS Infect Dis. 2023 Jan 13;9 (1) :122-139.