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Antibacterial agent 231

Antibacterial agent 231 (derivative 8) is an antimicrobial agent against multidrug-resistant Helicobacter pylori (H. pylori) with a minimum inhibitory concentration of 0.25–0.5 μg/mL. Antibacterial agent 231 directly targets the protein transposase subunit SecA and the outer membrane protein assembly factor BamD to inhibit the trafficking and assembly of bacterial outer membrane proteins (OMPs) . Antibacterial agent 231 can be used to study the effects of antibiotic treatment on intestinal microbial balance[1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-231.html

Smiles

COC1=C(OC/C=C/C)C=C2C(C(C(C/C=C/C)=C(C=CC(OC)=C3OC)C3=C4)=[N+]4CC2)=C1.[Br-]

Molecular Formula

C28H32BrNO4

Molecular Weight

526.46

References & Citations

[1]X Guo, et al. A deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori. Signal Transduction and Targeted Therapy 9, no. 1 (2024) : 183.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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