PRMT5-IN-23
PRMT5-IN-23 (compound 50) is an inhibitor of protein arginine methyltransferase 5 (PRMT5) with anti-tumor activity. PRMT5 is a type of protein arginine methyltransferase, and is a new anti-tumor target related to epigenetic modification[1].
Product Specifications
UNSPSC
12352209
Target
Histone Methyltransferase
Type
Peptides
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt5-in-23.html
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@H](CCCCC[C@@H](C(N[C@H](C(N[C@@H](C)C(N[C@@H](CC(C(O)=O)C(O)=O)C(N[C@H](C(N)=O)CCCCNC(NC2=CC3=C(C4(C5=C(OC6=C4C=CC(O)=C6)C=C(O)C=C5)OC3=O)C=C2)=S)=O)=O)=O)CC(O)=O)=O)NC7=O)C(N[C@@H](CCC(N)=O)C(N[C@H]7CC8=CC=C([N+]([O-])=O)C=C8)=O)=O)=O)=O)C
Molecular Formula
C75H91N15O25S
Molecular Weight
1634.68
References & Citations
[1]Fallot LB, et al. Structure-Activity Studies of 1H-Imidazo[4,5-c]quinolin-4-amine Derivatives as A3 Adenosine Receptor Positive Allosteric Modulators. J Med Chem. 2022 Nov 24;65 (22) :15238-15262.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
PRMT5
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUM0637-50 1x 50 µL
Renal Cell Carcinoma (Carbonic Anhydrase IX) (PN-15), 1mg/mL
Sign In for Pricing
View Details 
HA725053 100 µL
Human IFN beta Recombinant Rabbit monoclonal Antibody
Sign In for Pricing
View Details 
![Perforin (PRF1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3D7]](https://cdn.genprice.uk/products/937/68dd1b89061270361ea21762/imageurl/ta814190am.webp)
TA814190AM 100 µL
Perforin (PRF1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3D7]
Sign In for Pricing
View Details 
E-BC-K016-S-01 50 Assays (38 samples)
Uric Acid (UA) Colorimetric Assay Kit
Sign In for Pricing
View Details