PRMT5-IN-23
Product Specifications
UNSPSC Description
PRMT5-IN-23 (compound 50) is an inhibitor of protein arginine methyltransferase 5 (PRMT5) with anti-tumor activity. PRMT5 is a type of protein arginine methyltransferase, and is a new anti-tumor target related to epigenetic modification[1].
Target Antigen
Histone Methyltransferase
Type
Peptides
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt5-in-23.html
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@H](CCCCC[C@@H](C(N[C@H](C(N[C@@H](C)C(N[C@@H](CC(C(O)=O)C(O)=O)C(N[C@H](C(N)=O)CCCCNC(NC2=CC3=C(C4(C5=C(OC6=C4C=CC(O)=C6)C=C(O)C=C5)OC3=O)C=C2)=S)=O)=O)=O)CC(O)=O)=O)NC7=O)C(N[C@@H](CCC(N)=O)C(N[C@H]7CC8=CC=C([N+]([O-])=O)C=C8)=O)=O)=O)=O)C
Molecular Weight
1634.68
References & Citations
[1]Fallot LB, et al. Structure-Activity Studies of 1H-Imidazo[4,5-c]quinolin-4-amine Derivatives as A3 Adenosine Receptor Positive Allosteric Modulators. J Med Chem. 2022 Nov 24;65(22):15238-15262.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P3822/PRMT5-IN-23-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P3822/
Clinical Information
No Development Reported
Curated Selection
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