PI3kδ inhibitor 1
PI3kδ inhibitor 1 is a potent and selective PI3Kδ inhibitor with an IC50 of 3.8 nM.
Product Specifications
CAS Number
1332075-63-4
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3k_delta_-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
CC(O)(C1CCN(CC2=NC3=C(N4CCOCC4)N=C(C5=C(F)C=CC6=C5C=CN6)N=C3C=C2)CC1)C
Molecular Formula
C28H33FN6O2
Molecular Weight
504.60
References & Citations
[1]Sutherlin DP, et al. Potent and selective inhibitors of PI3Kδ: obtaining isoform selectivity from the affinity pocket and tryptophan shelf. Bioorg Med Chem Lett. 2012 Jul 1;22 (13) :4296-302.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kδ
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2368295 100 µL
Galectin 3 Mouse Monoclonal Antibody (PerCP-Cy5.5)
Sign In for Pricing
View Details 
OR1023496 1 Each
Poly (Ethylene Glycol) 4-Nonphenyl 3-Sulfamoyl Ether Potassium Salt
Sign In for Pricing
View Details QP8105-ec-50ug 50ug
Recombinant Human CCR4-NOT transcription complex subunit 8 Protein, GST, E.coli-50ug
Sign In for Pricing
View Details