PSI-352938
Product Specifications
UNSPSC Description
PSI-352938 (PSI-938) is a hepatitis C virus (HCV) nucleotide inhibitor[1].
Target Antigen
HCV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/PSI-352938.html
Solubility
10 mM in DMSO
Smiles
F[C@]1(C)[C@H](O[P@]2(OC(C)C)=O)[C@@H](CO2)O[C@H]1N3C(N=C(N)N=C4OCC)=C4N=C3
Molecular Weight
431.36
References & Citations
[1]Lam AM, et al. Hepatitis C virus nucleotide inhibitors PSI-352938 and PSI-353661 exhibit a novel mechanism of resistance requiring multiple mutations within replicon RNA. J Virol. 2011 Dec;85(23):12334-42.|[2]Lam AM, et al. Inhibition of hepatitis C virus replicon RNA synthesis by PSI-352938, a cyclic phosphate prodrug of β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methylguanosine. Antimicrob Agents Chemother. 2011 Jun;55(6):2566-75.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15231/PSI-352938-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15231/
Clinical Information
Phase 1
CAS Number
1199809-32-9
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