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Thymidine 5′-monophosphate p-nitrophenyl ester (sodium)

Thymidine 5′-monophosphate p-nitrophenyl ester sodium (Compound 2a) is the derivative of thymidine 5'-phosphate (TMP) . Thymidine 5′-monophosphate p-nitrophenyl ester sodium is potential as an antitumor prodrug[1].

Product Specifications

CAS Number

98179-10-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/thymidine-5-monophosphate-p-nitrophenyl-ester-sodium.html

Purity

99.85

Solubility

H2O : 116.67 mg/mL (ultrasonic)

Smiles

O=C(N1)N([C@@H]2O[C@H](COP(OC3=CC=C([N+]([O-])=O)C=C3)(O[Na])=O)[C@@H](O)C2)C=C(C)C1=O

Molecular Formula

C16H17N3NaO10P

Molecular Weight

465.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Chawla RR, et al., Bis (m-nitrophenyl) and bis (p-nitrophenyl) esters and the phosphorodiamidate of thymidine 5'-phosphate as potential sources of intracellular thymidine 5'-phosphate in mouse cells in culture. J Med Chem. 1984 Dec;27 (12) :1733-6.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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