Linaclotide (Standard)
Linaclotide (Standard) is the analytical standard of Linaclotide. This product is intended for research and analytical applications. Linaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.
Product Specifications
CAS Number
851199-59-2
UNSPSC
12352209
Target
Guanylate Cyclase; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/linaclotide-standard.html
Smiles
O=C([C@@H](NC([C@@](CSSC[C@@H]1N)([H])NC([C@@](CSSC[C@H](N2)C(N[C@H](C(O)=O)CC3=CC=C(O)C=C3)=O)([H])NC([C@@H](NC([C@@H](N4)CCC(O)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)CC(N)=O)N6[C@@](C(N[C@H](C(N[C@](CSSC[C@](C4=O)([H])NC1=O)([H])C(NC(C(NCC2=O)=O)[C@H](O)C)=O)=O)C)=O)([H])CCC6
Molecular Formula
C59H79N15O21S6
Molecular Weight
1526.74
References & Citations
[1]Bryant AP, et al. Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract. Life Sci. 2010 May 8;86 (19-20) :760-5.|[2]Love BL, et al. Linaclotide: a novel agent for chronic constipation and irritable bowel syndrome. Am J Health Syst Pharm. 2014 Jul 1;71 (13) :1081-91.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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