(S) -Rasagiline mesylate

(S) -Rasagiline (TVP1022) mesylate is the relatively inactive S-enantiomer form of Rasagiline mesylate. Rasagiline mesylate is a highly potent selective irreversible MAO inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively[1]. (S) -Rasagiline mesylate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[202464-88-8]

Product Name Alternative

TVP1022 (mesylate) ; S-PAI mesylate

UNSPSC

12352005

Hazard Statement

H302-H319-H332-H372-H400

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/TVP1022-mesylate.html

Solubility

10 mM in DMSO

Smiles

C#CCN[C@H]1CCC2=CC=CC=C21.OS(=O)(C)=O

Molecular Formula

C13H17NO3S

Molecular Weight

267.34

Precautions

P260-P261-P264-P270-P271-P273-P280-P304+P340-P305+P351+P338-P330-P391-P501

References & Citations

[1]M B Youdim, et al. Rasagiline [N-propargyl-1R (+) -aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol. 2001 Jan;132 (2) :500-6.