Creatine (monohydrate)

Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[1].

Product Specifications

CAS Number

[6020-87-7]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Akt; Endogenous Metabolite; PI3K

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; PI3K/Akt/mTOR

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/creatine-monohydrate.html

Purity

99.98

Solubility

H2O : 16.67 mg/mL (ultrasonic)

Smiles

O=C(O)CN(C(N)=N)C.[H]O[H]

Molecular Formula

C4H11N3O3

Molecular Weight

149.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Nouioua S, et al. Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency. Neuromuscul Disord. 2013 Aug;23 (8) :670-4.|[2]Gerber I, et al., Stimulatory effects of creatine on metabolic activity, differentiation and mineralization of primary osteoblast-like cells in monolayer and micromass cell cultures. Eur Cell Mater. 2005 Jul 15;10:8-22.|[3]Guidi C, et al., Differential effect of creatine on oxidatively-injured mitochondrial and nuclear DNA. Biochim Biophys Acta. 2008 Jan;1780 (1) :16-26.|[4]Cunha MP, et al., Antidepressant-like effect of creatine in mice involves dopaminergic activation. J Psychopharmacol. 2012 Nov;26 (11) :1489-501.|[5]ARRUDA I F S, et al. Histological effects of Creatine monohydrate supplementation on muscle tissue in Wistar rats[J]. Modern Medicine, 2023, 30 (2) .