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BPR1J-097

Product Specifications

UNSPSC Description

BPR1J-097 is a novel potent FLT3 inhibitor with an IC50 of 11 nM.

Target Antigen

FLT3

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/BPR1J-097.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=NNC(C2=CC=CC(NS(=O)(C3=CC=CC=C3)=O)=C2)=C1)C4=CC=C(N5CCN(C)CC5)C=C4

Molecular Weight

516.61

References & Citations

[1]Lin WH, et al. BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML. Br J Cancer. 2012 Jan 31;106(3):475-81.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-13537/BPR1J-097-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-13537/

Clinical Information

No Development Reported

CAS Number

1327167-19-0

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