BPR1J-097
BPR1J-097 is a novel potent FLT3 inhibitor with an IC50 of 11 nM.
Product Specifications
CAS Number
[1327167-19-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H320-H335
Target
FLT3
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/BPR1J-097.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NNC(C2=CC=CC(NS(=O)(C3=CC=CC=C3)=O)=C2)=C1)C4=CC=C(N5CCN(C)CC5)C=C4
Molecular Formula
C27H28N6O3S
Molecular Weight
516.61
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Lin WH, et al. BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML. Br J Cancer. 2012 Jan 31;106 (3) :475-81.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13537/BPR1J-097-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13537/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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