L-Valine-d8

L-Valine-d8 is a deuterated form of L-Valine (HY-N0717) . L-Valine ((S) -Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase[1][2][3].

Product Specifications

CAS Number

[35045-72-8]

Product Name Alternative

L-VALINE-2,3,4,4,4,5,5,5-d8

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Akt; Arginase; Bacterial; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR

Field of Research

Infection

Purity

99.84

Solubility

H2O : ≥ 41.67mg/mL

Smiles

[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])[C@@](N)([2H])C(O)=O

Molecular Formula

C5H3D8NO2

Molecular Weight

125.20

Precautions

H302, H315, H319, H335

References & Citations

[1]K Kirubavathi, et al. Synthesis, growth, structural, spectroscopic and optical studies of a new semiorganic nonlinear optical crystal: L-valine hydrochloride. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69 (4) :1283-6. |[2]Zhang BH, et al., L-valine, an antialgal amino acid from Streptomyces jiujiangensis JXJ 0074 (T) . Appl Microbiol Biotechnol. 2016 May;100 (10) :4627-36. |[3]Chen XH, et al., Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207.