Seco-Duocarmycin TM
Seco-Duocarmycin TM is a DNA alkylator agent belonging to Duocarmycins family that inhibits DNA synthesis. Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates (ADC) [1].
Product Specifications
CAS Number
[236102-87-7]
UNSPSC
12352203
Target
ADC Payload; DNA Alkylator/Crosslinker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/seco-duocarmycin-tm.html
Solubility
10 mM in DMSO
Smiles
OC[C@H]1C2=C(C=CC=C3)C3=C(O)C=C2N(C(C4=CC(C=C(OC)C(OC)=C5OC)=C5N4)=O)C1
Molecular Formula
C25H24N2O6
Molecular Weight
448.47
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130083/Seco-Duocarmycin-TM-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130083/
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Duocarmycins
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