NO2-SPP-sulfo-Me
NO2-SPP-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC) [1].
Product Specifications
CAS Number
[890409-87-7]
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/no2-spp-sulfo-me.html
Solubility
10 mM in DMSO
Smiles
CC(SSC1=NC=C([N+]([O-])=O)C=C1)CCC(ON2C(C(S(=O)(C)=O)CC2=O)=O)=O
Molecular Formula
C15H17N3O8S3
Molecular Weight
463.51
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Robert J. Lutz, et al.Methods for decreasing ocular toxicity of antibody drug conjugates. WO2012138749A1.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Disulfide Cleavable Linker
Curated Selection
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