SPDB-sulfo
SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) [1].
Product Specifications
CAS Number
[1628113-16-5]
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/spdb-sulfo.html
Solubility
10 mM in DMSO
Smiles
O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCSSC2=NC=CC=C2
Molecular Formula
C13H14N2O7S3
Molecular Weight
406.45
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Tinya Abrams, et al. ANTIBODY DRUG CONUGATES. US20140271688A1.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Disulfide Cleavable Linker
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