Aloc-D-Ala-Phe-Lys (Aloc) -PAB-PNP
Aloc-D-Ala-Phe-Lys (Aloc) -PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Product Specifications
CAS Number
[253863-34-2]
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aloc-d-ala-phe-lys-aloc-pab-pnp.html
Solubility
10 mM in DMSO
Smiles
O=[N+]([O-])C(C=C1)=CC=C1OC(OCC(C=C2)=CC=C2NC([C@H](CCCCNC(OCC=C)=O)NC([C@@H](NC([C@@H](C)NC(OCC=C)=O)=O)CC3=CC=CC=C3)=O)=O)=O
Molecular Formula
C40H46N6O12
Molecular Weight
802.83
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Protease Cleavable Linker
Curated Selection
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