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PDdEC-NB

PDdEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC) .

Product Specifications

CAS Number

1956318-90-3

UNSPSC

12352203

Hazard Statement

H302-H315-H319-H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pddec-nb.html

Purity

97.63

Solubility

10 mM in DMSO

Smiles

O=C(OC1=CC=C([N+]([O-])=O)C=C1)OCC(SSC2=NC=CC=C2)(C)C

Molecular Formula

C16H16N2O5S2

Molecular Weight

380.44

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Flygare, John, et al. Anthracycline disulfide intermediates, antibody-​drug conjugates and methods.WO 2016040825 A1 20160317.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker; Disulfide Cleavable Linker

Available Sizes

Frequently Asked Questions

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