Fmoc-Val-Cit-PAB-MMAE
Fmoc-Val-Cit-PAB-MMAE consists the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE) . Fmoc-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC.
Product Specifications
CAS Number
[1350456-56-2]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Fmoc-Val-Cit-PAB-MMAE.html
Purity
98.89
Solubility
DMSO : ≥ 30 mg/mL
Smiles
O=C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@]([C@@H](C)CC)([H])[C@H](OC)CC(N(CCC2)[C@]2([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C3=CC=CC=C3)O)=O)=O)=O)=O)=O)C=C1)=O)=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
Molecular Formula
C73H104N10O14
Molecular Weight
1345.67
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Auristatin
Available Sizes
Curated Selection
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