Deltasonamide 2
Deltasonamide 2 is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM[1].
Product Specifications
CAS Number
2088485-34-9
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/deltasonamide-2.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(S(=O)(N(CC2=CC=C(Cl)C=C2)C3CCCC3)=O)C=C1)(N([C@H]4CC[C@H](N)CC4)CC5=NC(NC)=NC=C5)=O
Molecular Formula
C30H39ClN6O4S2
Molecular Weight
647.25
References & Citations
[1]Klein CH, et al. PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell linesharboring oncogenic KRas. Int J Cancer. 2019 Feb 15;144 (4) :767-776.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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