NGR peptide
NGR peptide containing the Asn-Gly-Arg (NGR) motif. NGR peptide binds to APN/CD13. NGR peptide is directly conjugated to imaging agents that can be used for tumor imaging[1][2].
Product Specifications
CAS Number
651328-78-8
UNSPSC
12352209
Target
Aminopeptidase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ngr-peptide.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CS)C(NCC(O)=O)=O)[C@H](CCCNC(N)=N)NC(CNC([C@H](CC(N)=O)NC([C@@H](N)CS)=O)=O)=O
Molecular Formula
C20H36N10O8S2
Molecular Weight
608.69
References & Citations
[1]Wang RE, et al. Development of NGR peptide-based agents for tumor imaging. Am J Nucl Med Mol Imaging. 2011;1 (1) :36-46. |[2]Ma W, et al. Biodistribution and SPECT imaging study of (99m) Tc labeling NGR peptide in nude mice bearing human HepG2 hepatoma. Biomed Res Int. 2014;2014:618096.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
CD13
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