CM-579
CM-579 is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells[1].
Product Specifications
CAS Number
[1846570-40-8]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
DNA Methyltransferase; Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CM-579.html
Solubility
10 mM in DMSO
Smiles
CN1CCC(CNC2=CC(C3=CC=C(C)O3)=NC4=CC(OCCCN5CCCC5)=C(OC)C=C24)CC1
Molecular Formula
C29H40N4O3
Molecular Weight
492.65
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117421/CM-579-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117421/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DNA Methyltransferase; DNMT1; DNMT3; EHMT2/G9a/KMT1C
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) AIP1-2 Polyclonal Antibody
