(S, R, S) -AHPC-C2-amide-benzofuranylmethyl-pyridine
(S, R, S) -AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual target PROTAC that can not only target to the ubiquitination and degradation of Smad3 but also improve the HIF-α protein level. (S, R, S) -AHPC-C2-amide-benzofuranylmethyl-pyridine has a multi-path anti-fibrosis function and a renal protection function for research of renal anemia. (S, R, S) -AHPC-C2-amide-benzofuranylmethyl-pyridine can be used for research on prostate cancer and other cancers[1][2].
Product Specifications
CAS Number
[2347517-69-3]
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase; PROTACs; TGF-beta/Smad
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; PROTAC; Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-c2-amide-benzofuranylmethyl-pyridine.html
Purity
98.62
Solubility
DMSO : ≥ 170 mg/mL
Smiles
O=C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)[C@H](C(C)(C)C)NC(CCC(NC(C4=CN=CC=C4)C5=CC6=CC=CC=C6O5)=O)=O
Molecular Formula
C41H46N6O6S
Molecular Weight
750.91
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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