Fmoc-Phe-Lys (Boc) -PAB-PNP
Fmoc-Phe-Lys (Boc) -PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Product Specifications
CAS Number
[1646299-50-4]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Fmoc-Phe-Lys_Boc_-PAB-PNP.html
Purity
98.67
Solubility
DMSO : 6 mg/mL (ultrasonic)
Smiles
O=C(OC1=CC=C([N+]([O-])=O)C=C1)OCC(C=C2)=CC=C2NC([C@H](CCCCNC(OC(C)(C)C)=O)NC([C@H](CC3=CC=CC=C3)NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O)=O)=O
Molecular Formula
C49H51N5O11
Molecular Weight
885.96
Precautions
H302, H315, H319, H335
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Protease Cleavable Linker
Curated Selection
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