Carnostatine
Carnostatine (SAN9812) is a potent and selective carnosinase 1 (CN1) inhibitor with a Ki of 11 nM for human recombinant CN1. Carnostatine (SAN9812) can be used for the treatment of diabetic nephropathy (DN) [1].
Product Specifications
Product Name Alternative
SAN9812
UNSPSC
12352209
Target
Carnosine-cleaving Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Carnostatine.html
Solubility
10 mM in DMSO
Smiles
OC([C@@H](NC([C@@H](O)CCN)=O)CC1=CNC=N1)=O
Molecular Formula
C10H16N4O4
Molecular Weight
256.26
References & Citations
[1]Qiu J, et al. Identification and characterisation of carnostatine (SAN9812), a potent and selective carnosinase (CN1) inhibitor with in vivo activity. Amino Acids. 2019 Jan;51 (1) :7-16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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