RO5487624
Product Specifications
UNSPSC Description
RO5487624, an analogue of RO5464466 (HY-120690), is an orally active hemagglutinin (HA) inhibitor of influenza H1N1 viruses that abolishes influenza virus fusion by blocking HA conformational changes in low pH environments. RO5487624 displays a protective effect on mice that are lethally challenged with influenza H1N1 virus[1].
Target Antigen
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ro5487624.html
Smiles
O=S(C1=CC(NC[C@]2(C)CC(C)(C)C[C@H](O)C2)=CC=C1Cl)(N)=O
Molecular Weight
360.90
References & Citations
[1]Zhu L, et al. Inhibition of influenza A virus (H1N1) fusion by benzenesulfonamide derivatives targeting viral hemagglutinin. PLoS One. 2011;6(12):e29120.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116182/RO5487624-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116182/
Clinical Information
No Development Reported
CAS Number
1399103-28-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
