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Huanglongmycin N

Product Specifications

UNSPSC Description

Huanglongmycin N is a DNA topoisomerase I inhibitor (EC50 = 14 μM).

Target Antigen

Topoisomerase

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/huanglongmycin-n.html

Solubility

10 mM in DMSO

Smiles

OC1=C(CC)C=CC(C2=O)=C1C(C3=C2C=C(C)C(C(C)=O)=C3O)=O

Molecular Weight

324.33

References & Citations

[1]Zhu S, et al. Discovery of a DNA Topoisomerase I Inhibitor Huanglongmycin N and Its Congeners from Streptomyces sp. CB09001. J Org Chem. 2021 Dec 3;86(23):16675-16683.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N10115/Huanglongmycin-N-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N10115/

Clinical Information

No Development Reported

CAS Number

2881024-09-3

Available Sizes

Curated Selection

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