Huanglongmycin N
Product Specifications
UNSPSC Description
Huanglongmycin N is a DNA topoisomerase I inhibitor (EC50 = 14 μM).
Target Antigen
Topoisomerase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/huanglongmycin-n.html
Solubility
10 mM in DMSO
Smiles
OC1=C(CC)C=CC(C2=O)=C1C(C3=C2C=C(C)C(C(C)=O)=C3O)=O
Molecular Weight
324.33
References & Citations
[1]Zhu S, et al. Discovery of a DNA Topoisomerase I Inhibitor Huanglongmycin N and Its Congeners from Streptomyces sp. CB09001. J Org Chem. 2021 Dec 3;86(23):16675-16683.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N10115/Huanglongmycin-N-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N10115/
Clinical Information
No Development Reported
CAS Number
2881024-09-3
Available Sizes
Curated Selection
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