C (phg-isoDGR- (NMe) k)
C (phg-isoDGR- (NMe) k) is a selective and potent α5β1-integrin ligand with an IC50 of 2.9 nM[1].
Product Specifications
CAS Number
[1844830-65-4]
UNSPSC
12352200
Target
Integrin
Type
Biochemical Assay Reagents
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c_phg-isoD-G-R-_NMe_k_.html
Solubility
10 mM in DMSO
Smiles
O=C(CNC(C[C@@H](C(O)=O)NC([C@@H](C1=CC=CC=C1)NC([C@H]2CCCCN)=O)=O)=O)N[C@@H](CCCNC(N)=N)C(N2C)=O
Molecular Formula
C27H41N9O7
Molecular Weight
603.67
References & Citations
[1]Kapp TG, et al. N-Methylation of isoDGR Peptides: Discovery of a Selective α5β1-Integrin Ligand as a Potent Tumor Imaging Agent. J Med Chem. 2018 Mar 22;61 (6) :2490-2499.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Curated Selection
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