Umbellulone
Product Specifications
UNSPSC Description
Umbellulone is an active constituent of the leaves of Umbellularia californica. Umbellulone stimulates the TRPA1 channel in a subset of peptidergic, nociceptive neurons, activating the trigeminovascular system via this mechanism[1].
Target Antigen
TRP Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/umbellulone.html
Smiles
O=C1[C@@]2(C(C)C)C[C@@]2([H])C(C)=C1
Molecular Weight
150.221
References & Citations
[1]Nassini R, et al. The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. Brain. 2012 Feb;135(Pt 2):376-90.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-135013/Umbellulone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-135013/Umbellulone-SDS-MedChemExpress.pdf
CAS Number
546-78-1
Available Sizes
Curated Selection
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