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Sinapaldehyde

Sinapaldehyde is a methoxyphenol and a selective COX-2 inhibitor (IC50: 47.8 µM) that can be extracted from various plants. Sinapaldehyde has antibacterial, anti-inflammatory, and antioxidant activities. Sinapaldehyde can scavenge DPPH free radicals (IC50: 172 μM) . Sinapaldehyde is active against both Gram-negative and Gram-positive bacteria[1][2].

Product Specifications

CAS Number

4206-58-0

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; COX; Interleukin Related; JNK; NO Synthase; PERK; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sinapaldehyde.html

Purity

99.71

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C/C=C/C1=CC(OC)=C(O)C(OC)=C1

Molecular Formula

C11H12O4

Molecular Weight

208.21

Precautions

H302, H315, H319, H335

References & Citations

Rhodamnia Dumetorum

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

COX-2; IL-6

Available Sizes

Frequently Asked Questions

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