HIV-1 integrase inhibitor 4
HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM.
Product Specifications
CAS Number
[1638504-66-1]
UNSPSC
12352005
Target
HIV; HIV Integrase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/HIV-1_integrase_inhibitor_4.html
Solubility
10 mM in DMSO
Smiles
NC(C1=CC(CCS(=O)(C2=CC=CC=C2)=O)=CN=C1N3O)=C(C(NCC4=CC=C(F)C=C4F)=O)C3=O
Molecular Formula
C24H20F2N4O5S
Molecular Weight
514.50
References & Citations
[1]Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15;11 (4) :1074-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
Curated Selection
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