HIV-1 integrase inhibitor 3
HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM.
Product Specifications
CAS Number
[1638504-56-9]
UNSPSC
12352005
Target
HIV; HIV Integrase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/HIV-1_integrase_inhibitor_3.html
Solubility
10 mM in DMSO
Smiles
NC(C1=CC(CCCCCO)=CN=C1N2O)=C(C(NCC3=CC=C(F)C=C3F)=O)C2=O
Molecular Formula
C21H22F2N4O4
Molecular Weight
432.42
References & Citations
[1]Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15;11 (4) :1074-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
Curated Selection
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