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HIV-1 integrase inhibitor 3

HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM.

Product Specifications

CAS Number

[1638504-56-9]

UNSPSC

12352005

Target

HIV; HIV Integrase

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/HIV-1_integrase_inhibitor_3.html

Solubility

10 mM in DMSO

Smiles

NC(C1=CC(CCCCCO)=CN=C1N2O)=C(C(NCC3=CC=C(F)C=C3F)=O)C2=O

Molecular Formula

C21H22F2N4O4

Molecular Weight

432.42

References & Citations

[1]Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15;11 (4) :1074-81.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HIV-1

Curated Selection

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