Albanol B

Albanol B is an arylbenzofuran derivative which can be isolated from mulberries. Albanol B exhibits anti-Alzheimer's disease, anti-bacterial and antioxidant activities. Albanol B inhibits cancer cells proliferation, down-regulates CDK1 expression. Albanol B also induces cell cycle arrest at G2/M and apoptosis. And Albanol B induces mitochondrial ROS production and increases the phosphorylation levels of AKT and ERK1/2[1].

Product Specifications

CAS Number

[87084-99-9]

UNSPSC

12352005

Target

Akt; Apoptosis; Bacterial; CDK; ERK

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Cell Cycle/DNA Damage; MAPK/ERK Pathway; PI3K/Akt/mTOR; Stem Cell/Wnt

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/albanol-b.html

Purity

99.79

Solubility

10 mM in DMSO

Smiles

OC1=C(C=CC(O)=C1)[C@@]23C4=C(C5=CC=C(O)C=C5O3)C=C(C)C=C4C6=C(O)C=C(C(OC7=C8)=CC7=CC=C8O)C=C6O2

Molecular Formula

C34H22O8

Molecular Weight

558.53

References & Citations

[1]Phan TN, et al. Albanol B from Mulberries Exerts Anti-Cancer Effect through Mitochondria ROS Production in Lung Cancer Cells and Suppresses In Vivo Tumor Growth. Int J Mol Sci. 2020 Dec 14;21 (24) :9502.