ZINC05626394
ZINC05626394 is a cytochrome b5 reductase 3 inhibitor with activity by increasing nitric oxide bioavailability. ZINC05626394 may have potential applications in anti-cancer suppression, especially in combination with antibody drug conjugates (ADCs) and immune checkpoint inhibitors. The efficacy of ZINC05626394 may be limited by different mechanisms, including antigen-related resistance and failure of endocytosis[1].
Product Specifications
CAS Number
[189057-68-9]
UNSPSC
12352005
Hazard Statement
H302
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zinc05626394.html
Purity
99.8
Smiles
O=C(N1)C=C(NC1=S)CSC2=CC=CC=C2
Molecular Formula
C11H10N2OS2
Molecular Weight
250.34
Precautions
H302
References & Citations
[1]Mechanisms of Resistance to Antibody-Drug Conjugates
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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