Thalidomide-O-amido-PEG3-C2-NH2
Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
Product Specifications
CAS Number
[1957236-20-2]
Product Name Alternative
Cereblon Ligand-Linker Conjugates 3 ; E3 Ligase Ligand-Linker Conjugates 14
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/E3_Ligase_Ligand-Linker_Conjugates_21.html
Solubility
10 mM in DMSO
Smiles
NCCOCCOCCOCCNC(COC1=C(C2=CC=C1)C(N(C(CCC3=O)C(N3)=O)C2=O)=O)=O
Molecular Formula
C23H30N4O9
Molecular Weight
506.51
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Methods to induce targeted protein degradation through bifunctional molecules. WO 2017007612 A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
J Young Norell Select Series NMR Tube With 5mm NMR Valve 300mhz 7 Long
