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Anti-P-Cadherin Antibody

Mouse Monoclonal Antibody specific to Human P-cadherin

Product Specifications

Product Name Alternative

Placental cadherin, P-cadherin

Gene Name

CDH3

NCBI Gene ID

<a href="https://www.ncbi.nlm.nih.gov/gene/?term=CDH3">CDH3</a>

UniProt

P22223

Cellular Locus

Cell membrane; Single-pass type I membrane protein.

Host

Mouse

Reactivity

Human

Immunogen

Human epidermal carcinoma cell line A431.

Target Antigen

Cadherin-3

Target

P-Cadherin

Clonality

Monoclonal

Isotype

IgG1

Type

Antibody

Applications

WB, IHC, Inhibition

Field of Research

Cell adhesion

Purification Method

Purified by immunoaffinity chromatography

Dilution

Reconstitute in distilled water to the final desired concentration.

Format

Purified

Form

Lyophilized

Buffer

Phosphate Buffered Saline

Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Additionnal Information

Western Blotting: 5-10 ug/ml, non-reducing and non-heating conditions. <br><br>Immunohistochemistry: 5-10 ug/ml, frozen tissue sections. <br><br>Cell Contact Inhibition Assays: 100 ug/ml

Storage Conditions

Lyophilized antibody is stable at 4°C for 2 years. Store the reconstituted solution in aliquots at -20°C for one year or at 4°C for 6 months after addition of 0.1% sodium azide by the user. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.qedbio.com/wp-content/uploads/pdf/42028.pdf

Specificity

This antibody specifically reacts with human P-Cadherin, and inhibits P- Cadherin dependent cell-cell contact.

Formulation

10 mM PBS, pH 7.4, lyophilized

Buffer pH

pH 7.4

CAS Number

9007-83-4

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