What is the catalog number for GW3965?

The catalog number for GW3965 is HY-10627.

What sizes are available for GW3965?

GW3965 is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does GW3965 come in?

GW3965 is available in 6 different pack sizes.

GW3965 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GW3965?

GW3965 is manufactured by QuantiMol.

What is the estimated delivery time for GW3965?

Estimated delivery time for GW3965 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GW3965?

The safety data sheet for GW3965 is available here: http://file.medchemexpress.com/batch_PDF/HY-10627/GW3965-SDS-MedChemExpress.pdf.

GW3965

GW3965 is a potent, selective liver X receptor (LXR) agonist with EC50s of 190 nM and 30 nM for hLXRα and hLXRβ, respectively[1][2][3].

Product Specifications

CAS Number

405911-09-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

LXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/GW3965.html

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=C(C(F)(F)F)C=CC=C1CN(CC(C2=CC=CC=C2)C3=CC=CC=C3)CCCOC4=CC(CC(O)=O)=CC=C4

Molecular Formula

C33H31ClF3NO3

Molecular Weight

582.05

Precautions

H302, H315, H319, H335

References & Citations

[1]Mitro, Nico., et al. LXR and TSPO as new therapeutic targets to increase the levels of neuroactive steroids in the central nervous system of diabetic animals. Neurochemistry International (2012), 60 (6), 616-621.|[2]Guo, Deliang., et al. An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR-Dependent Pathway. Cancer Discovery (2011), 1 (5), 442-456.|[3]Spyridon, Michael., et al. LXR as a novel antithrombotic target. Blood (2011), 117 (21), 5751-5761.