Lintopride
Product Specifications
UNSPSC Description
Lintopride, a benzamide, is a potent 5HT-4 antagonist with moderate 5HT-3 antagonist properties. Lintopride increases gastric emptying, stimulates antral and duodenal motility and accelerates intestinal transit in animal. Lintopride significantly increases the lower oesophageal sphincter (LOS) basal tone[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Lintopride.html
Purity
96.38
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=NCCN1CC)C2=CC(Cl)=C(N)C=C2OC
Molecular Weight
310.78
References & Citations
[1]Delvaux M, et al. The effects of lintopride, a 5HT-4 antagonist, on oesophageal motility. Aliment Pharmacol Ther. 1995 Oct;9(5):563-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-U00121/Lintopride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-U00121/Lintopride-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
107429-63-0
Available Sizes
Curated Selection
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