Ko-3290

Ko-3290 is an antagonist of β-adrenoceptor, with cardioselectivity and antilipolytic effects in animals. Ko-3290 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

79848-61-6

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Ko-3290.html

Solubility

10 mM in DMSO

Smiles

CC(C)C(NC1=CC=C(OCC(O)CNC(C)(C)C#C)C(C#N)=C1)=O

Molecular Formula

C19H25N3O3

Molecular Weight

343.42

References & Citations

[1]T.H.PRINGLE, et al. The assessment of the-3-adrenoceptor blocking activity and cardioselectivity of Koe3290 innormal subjects. British Journal of Clinical Pharmacology (1987), 24 (5), 581-9