CGP48369
CGP48369 is a nonpeptidic angiotensin II receptor antagonist, used for anti-hypertensive research.
Product Specifications
CAS Number
135689-23-5
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/CGP48369.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(CCCC)=NC(CCCC)=C1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2
Molecular Formula
C26H30N6O
Molecular Weight
442.56
References & Citations
[1]Dohi Y, et al. Angiotensin blockade or calcium antagonists improve endothelial dysfunction in hypertension: studies in perfused mesenteric resistance arteries. J Cardiovasc Pharmacol. 1994 Sep;24 (3) :372-9.|[2]Tschudi MR, et al. Antihypertensive therapy augments endothelium-dependent relaxations in coronary arteries of spontaneously hypertensive rats. Circulation. 1994 May;89 (5) :2212-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
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