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Y1 receptor antagonist 1

Y1 receptor antagonist 1 (H 409-22 isomer) (Example 4) is a neuropeptide Y1 receptor antagonist. Y1 receptor antagonist 1 can be used for the study of cardiovascular diseases, such as vasoconstriction[1].

Product Specifications

CAS Number

[221697-09-2]

Product Name Alternative

H 409-22 (isomer)

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Neurokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/N-[_1R_-4-[_Aminoiminomethyl_amino]-1-[[[_1R_-1-_4-hydroxyphenyl_ethyl]amino]carbonyl]butyl]-_alpha_-phenylbenzeneacetamide.html

Purity

99.69

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](C(N[C@@H](C1=CC=C(O)C=C1)C)=O)CCCNC(N)=N)C(C2=CC=CC=C2)C3=CC=CC=C3

Molecular Formula

C28H33N5O3

Molecular Weight

487.59

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Nils-Åke Bergman, et al. New npy antagonists. WO1999015498A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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