LCB-2853

LCB-2853 is an antagonist of thromboxane A2 (TXA2) receptor, with antiplatelet and antithrombotic activities.

Product Specifications

CAS Number

[141335-10-6]

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/LCB-2853.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CC1=CC=C(CC2(CNS(=O)(C3=CC=C(Cl)C=C3)=O)CCCC2)C=C1

Molecular Formula

C21H24ClNO4S

Molecular Weight

421.94

References & Citations

[1]Depin JC, et al. Pharmacodynamics and antithrombotic effects after intravenous administration of the new thromboxane A2 receptor antagonist sodium 4-[[1-[[[ (4-chlorophenyl) sulfonyl]amino]methyl]cyclopentyl] methyl]benzeneacetate. Arzneimittelforschung. 1994 Nov;44 (11) :1203-7.|[2]Lardy C, et al. Antiaggregant and antivasospastic properties of the new thromboxane A2 receptor antagonist sodium 4-[[1-[[[ (4-chlorophenyl) sulfonyl]amino]methyl]cyclopentyl] methyl]benzeneacetate. Arzneimittelforschung. 1994 Nov;44 (11) :1196-202.