QF0301B
QF0301B is an α1 adrenergic receptor antagonist and a low α2 adrenoceptor, 5-HT2A, and histamine H1 receptor blocker.
Product Specifications
CAS Number
[149247-12-1]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/3,4-Dihydro-2-[2-[4-_2-methoxyphenyl_-1-piperazinyl]ethyl]-1_2H_-naphthalenone.html
Solubility
10 mM in DMSO
Smiles
O=C1C(CCN2CCN(C3=CC=CC=C3OC)CC2)CCC4=C1C=CC=C4
Molecular Formula
C23H28N2O2
Molecular Weight
364.48
References & Citations
[1]Orallo F, et al. In vivo and in vitro pharmacological studies of a new hypotensive compound (QF0301B) in rat: Comparison with prazosin, a known α1-adrenoceptor antagonist. Vascul Pharmacol. 2003 Feb;40 (2) :97-108.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; α adrenergic receptor
Available Sizes
Curated Selection
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