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LM-1484

LM-1484 is an antagonist of CysLT1 receptor and displays a higher affinity for 3H-LTC4 sites.

Product Specifications

CAS Number

197506-02-8

UNSPSC

12352005

Target

Leukotriene Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/LM-1484.html

Solubility

10 mM in DMSO

Smiles

O=C1C=C(C2=NN=NN2)OC3=C(/C=C/C4=CC=C(OCCCCC5=CC=CC=C5)C=C4)C=CC=C13

Molecular Formula

C28H24N4O3

Molecular Weight

464.52

References & Citations

[1]Ravasi S, et al. Pharmacological differences among CysLT (1) receptor antagonists with respect to LTC (4) and LTD (4) in human lung parenchyma. Biochem Pharmacol. 2002 Apr 15;63 (8) :1537-46.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

LTC4/CysLT2; LTD4/CysLT1

Frequently Asked Questions

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