LM-1484
LM-1484 is an antagonist of CysLT1 receptor and displays a higher affinity for 3H-LTC4 sites.
Product Specifications
CAS Number
197506-02-8
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/LM-1484.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=NN=NN2)OC3=C(/C=C/C4=CC=C(OCCCCC5=CC=CC=C5)C=C4)C=CC=C13
Molecular Formula
C28H24N4O3
Molecular Weight
464.52
References & Citations
[1]Ravasi S, et al. Pharmacological differences among CysLT (1) receptor antagonists with respect to LTC (4) and LTD (4) in human lung parenchyma. Biochem Pharmacol. 2002 Apr 15;63 (8) :1537-46.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LTC4/CysLT2; LTD4/CysLT1
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