Utibapril

Utibapril is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activities.

Product Specifications

CAS Number

[109683-61-6]

Product Name Alternative

FPL 63547

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Angiotensin-converting Enzyme (ACE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Utibapril.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H]1SC(C(C)(C)C)=NN1C([C@@H](N[C@H](C(OCC)=O)CCC2=CC=CC=C2)C)=O)O

Molecular Formula

C22H31N3O5S

Molecular Weight

449.56

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Buikema H, et al. Differential inhibition of plasma versus tissue ACE by utibapril: biochemical and functional evidence for inhibition of vascular ACE activity. J Cardiovasc Pharmacol. 1997 May;29 (5) :684-91.|[2]Carr RD, et al. Preferential biliary elimination of FPL 63547, a novel inhibitor of angiotensin-converting enzyme, in the rat. Br J Pharmacol. 1990 May;100 (1) :90-4.